Ships EU-wide from inside the EU · free from €200 · kits ship freeResearch use only · not for human or veterinary use
nordpeps
A 10 mg MOTS-c vial with a white nordpeps label
MOTS-C

MOTS-c 10-vial kit

from €319

+Details · certificate · FAQ ↓
MDPMitochondrial research

MOTS-c

Peptide encoded in mitochondrial DNA · kits of 10 or 30 vials

Mitochondrial-derived peptide (MDP)

MOTS-c is a short peptide coded by mitochondrial DNA, a so-called mitochondrial-derived peptide. Researchers study it in cell metabolism and mitochondrial signalling.

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  • Neutral outer box. No product names and no logo on the outside.
Certificates Per batch
Kit 10 or 30 vials
Dispatch 24–48 h

Research use only: laboratory and in-vitro work. Not for use in people or animals, and not for diagnostics.

Datasheet · MOTS-c

MOTS-c

Peptide encoded in mitochondrial DNA · kits of 10 or 30 vials

In stock
Category
Longevity
Vial sizes
10 · 40 mg
Sold as
10 or 30 vials
Vial size
Kit size
MOTS-c: price per vial and per kit
SizePer vial10-vial kit30-vial kit
10 mg€31.90
40 mg€47.90
€319


  • Price shown is for the full kit
  • Every kit ships free
  • Dispatched 24–48 h after payment, tracked

Delivery: €14.50 parcel locker · €19.50 address · free from €200 and on every kit

Ships EU-wide from inside the EULeaves us in 24–48 hKits ship free10- or 30-vial kitsSealed freeze-dried vials
Certificate of Analysis
On request

MOTS-c

Certificate for the current batch, emailed on request

About MOTS-c

MOTS-c has 16 amino acids and is encoded in the mitochondrial genome. It was among the first mitochondrial-derived peptides described. Metabolic and mitochondrial-signalling studies use it.

MOTS-c comes in sealed kits of 10 or 30 freeze-dried vials. Certificates from an independent third-party laboratory are published per batch on /certificates as they become available. For laboratory and in-vitro research only.

Mechanism of action

MOTS-c is a 16-residue peptide coded in mitochondrial DNA, inside the 12S rRNA gene. It was one of the first mitochondrial-derived peptides on record. Papers connect it to AMPK signalling and to the folate–methionine cycle.

Under metabolic stress it has been reported to travel to the nucleus. There, according to the literature, it affects nuclear gene expression. A signal running from mitochondria to nucleus is unusual. That is why researchers treat it as its own kind of tool, not one more receptor ligand.

A short summary of published work, given as research context. It makes no therapeutic claim.

What published studies show

MOTS-c was first characterised in a 2015 Cell Metabolism paper, with metabolic effects in animal models. A 2023 review in Frontiers in Endocrinology gathers what has been published since.

Research focuses on mitochondrial signalling, insulin sensitivity and exercise biology. All of it is preclinical. No approved medicine anywhere contains MOTS-c.

Written for education from published papers. It promises no result to anyone who buys, and NordPeps sells MOTS-c for laboratory research only.

Storage & handling

Unopened vials. Store at 2–8 °C. For long periods, −20 °C or colder. Room temperature is fine in transit, but it is not a way to store a peptide.

After reconstitution. Refrigerate at 2–8 °C. Do not freeze: ice crystals break the peptide down for good. In bacteriostatic water (0.9% benzyl alcohol), labs usually work through a vial within about 30 days. With plain sterile water, the window is 24–48 hours.

Keep vials closed and out of the light. If you hold frozen stock, thaw it as few times as you can; each cycle loses some activity.

Reconstitution calculator: concentration and draw volume →

Specifications

TypeMitochondrial-derived peptide
Research areaLongevity & Cellular Energy
Vial options10 · 40 mg per vial
Supplied asKit of 10 or 30 freeze-dried vials
StateFreeze-dried powder, sterile-filtered
CAS1627580-64-6
MW≈ 2175 g/mol
FormulaC101H152N28O22S2
Keep at2–8 °C; −20 °C for long-term
TestingIndependent third-party laboratory, one certificate per batch as it becomes available
CertificatesPublished per batch on /certificates when available
MOTS-c certificatesCertificates, batch by batchCertificates from an independent third-party laboratory are published per batch on /certificates as they become available.Open the certificates page →

References & research

Peer-reviewed sources on PubMed, listed for background reading. Citing a paper is not a claim that NordPeps products do anything clinically.

  1. MOTS-c, a mitochondrial-derived peptide, in metabolic homeostasis, obesity and insulin resistance (PubMed 25738459)
  2. MOTS-c as a candidate for therapeutic research (PubMed 36761202)

MOTS-c: common questions

How much does MOTS-c cost?

A 10-vial kit costs €319 (10 mg) or €479 (40 mg). A 30-vial kit costs three times as much (€957 or €1,437). Delivery is free on every kit, to all 27 EU countries.

Is there a certificate for this compound?

Certificates from an independent third-party laboratory are published per batch on /certificates as they become available.

What counts as a mitochondrial-derived peptide?

A short peptide coded by mitochondrial DNA instead of nuclear DNA. MOTS-c is one of the most studied, and metabolism labs use it as a research tool.

Why kits of 10 vials?

We sell this compound only in sealed kits of 10 identical vials, or 30. A 10-vial kit is the smallest order.

How do I store MOTS-c?

Unopened: 2–8 °C; for long stretches, −20 °C. Reconstituted: in the fridge, never frozen. Details are under storage and handling.

How is the concentration set?

By the volume of bacteriostatic water you add, not by the vial size alone. Enter the vial size and the diluent volume in the reconstitution calculator and it gives you the concentration.

Has any regulator approved MOTS-c?

No. The literature is preclinical and no medicine containing MOTS-c has been approved. “Research use only” means exactly that: the science is still in progress.

Sealed kits, dispatched inside the EU.

Kits leave us 24–48 hours after payment, in a plain box with tracking. Delivery stays within the EU. Laboratory research use only.

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